Translation form of depot fat in starvation.

Gordon et all-3 suggested that the transport of depot fat to the site of utilization probably takes place in the form of free fatty acid (unesterified fatty acid). Under both normal and abnormal circumstances, the amount of free fatty acid is very small in the serum and liver occupying only 1/4-1/5 of triglyceride or phospholipid. The portion derived from dietary fat is transported mainly in the lymph and then in the blood in the form of triglyceride (chylomicron) to be deposited as it is. We have therefore used fasting albino rats to measure triglyceride and free fatty acid in the serum and liver, suggesting thereby the transport of depot fatty acid in the form of triglyceride instead of free fatty aid.4 Further experiments have revealed the occurrence of transportation in the form of a low density lipoprotein, as reported below.